Melatonin in dermatology

In the dermatological field, the first choice route of administration is undoubtedly the topical one and melatonin represents a good candidate for transcutaneous absorption, considering its low molecular weight (MW = 232.27), the short half-life in plasma and a favorable octanol: water partition coefficient (log P = 1.20). With oral intake ...

Melatonin and skin

The main function of the skin of being a protective barrier between the external and internal environment makes it particularly important for preserving the homeostasis of the whole organism. Being constantly subject to the attack of chemical, biological or mechanical insults, the skin has developed unique properties in effectively counteracting these stress factors. First of all, it has the ability ...